The "Can't Hold Us" rapper, who took home four Grammys at this year's show, was battling a drug addiction just five years ago that nearly cost him his career.
In a special for MTVU's "Half of Us" campaign, Macklemore opened up about his past struggles with drugs, saying, "[When] I actually drank for the first time, I was by myself."
"This is an indicator of who I was, from the jump," he went on. "After school, by myself [at] 13 years old, maybe 14."
The Seattle native said the first time he drank he took 12 shots by himself and felt like he couldn't stop.
That eventually led him to skipping classes to smoke weed, which inhibited his ability to write rhymes because his "mind was blank."
After realizing he needed to lay off the drugs and alcohol if he wanted to pursue a music career, he got sober...but it only lasted about a month.
Next, he dabbled in Oxycontin, calling it one of the "most intense" drugs he's ever taken.
He wasn't able to get fully sober until his father talked him into going to rehab when he was 25.
"If it wasn't for that rehab center, I probably wouldn't have been here," he continued. "In terms of recovery, it has been very important for me to be a part of a recovery community, to actively be around my people because they understand me. They get it."
See Macklemore's full story in the clip below.