The event was organized by the TLC member, who herself is diagnosed with sickle cell anemia. Celebrity charity video app Chideo pitched in to help and Vampire Diaries star Kat, Grammy winning singers Raphael Saadiq and Faith performed for the cause, too.
T-Boz was the star of the night though, singing her hits "Waterfalls," "Unpretty," and "Baby, Baby, Baby" for the small, intimate crowd. She ended the night in tears, thanking everyone for the beautiful turnout.
"I had a dream, I literally saw [Saadiq] standing on the left side of me, and that's where he's standing today, so it's like my dream is really coming true," T-Boz told The Hollywood Reporter of making the concert a reality.
"When you have charity events, people feel bad right then, and then go on to the next thing. ... [A charity] concert is something you'd do in your free time anyway, and it's for a good cause. You can't get any better than that. It's win-win."
While at the show, Kat told us all about her latest single "1991" and how it samples TLC's 1992 hit "What About Your Friends.' She was as excited to perform with one of her idols, as we were to meet her.
"I've been wanting to do something with her for a really long time," she said. "She invited me to perform and I'm still not really believing I'm here."
Both T-Boz and Kat killed their performances. Faith sang her heart out, too. We left that place feeling proud to be a woman and with every TLC bumpin' tune in our heads.
Check out footage from T-Boz's Sickle Cell Anemia charity show, below.