We've pretty much seen every one of them over the years, from Candace Cameron Bure to Jodie Sweetin – and, of course, the Olsen twins (though it's unclear yet if they'll reprise their role as Michelle Tanner in this series).
But how about the boys who played twins Nicky and Alex Katsopolis, the kids of the adorable super-couple, Uncle Jesse and Aunt Becky, played by John Stamos and Lori Loughlin?
They are definitely returning to the new series – and, yeah, they're all grown up now.
Twins Blake Tuomy-Wilhoit and Dylan Tuomy-Wilhoit, now 24-years-old, confirmed they will be on the series, taking to Instagram to show off pics of the first episode's script, titled, "Our Very First Show, Again."
Dylan captioned the pic "What?," while Blake wrote: "Its Nicky time!"
And here they are, all grown up: