Asked whether she's the type of person to take such social media abuse lying down, Lawrence replied with a totally spontaneous, "F**k it."
"I'm gonna do something about it," she said, before storming offstage and grabbing a can of conveniently located spray paint. A bus then rolled into view to reveal her plan: defacing her co-star's likeness on a massive "Passengers" ad.
As Lawrence scribbled over Pratt's face, Kimmel joined in, too.
"Look, I have 'ass' here," said the 49-year-old professional late night host.
Watch the whole clip above.
"Passengers" hits theaters Dec. 21.